• G. Belov International School of Medicine of the International University of Kyrgyzstan
  • T. Uzakov Kyrgyz State Medical Institute for Retraining and Advanced Studies
  • J. Chyngyshova Kyrgyz State Medical Institute for Retraining and Advanced Studies


surgical site infection, rehabilitation, chitosan, photomodulation, physical exercise


In an experiment on 30 white rats, the effect of the chitosan complex, photomodulation with methylineic blue and physical exercises on postoperative wound healing was studied. The animals are divided into 5 groups of 6 rats. Group 1 - intact animals. For other groups, hair was cut on the lateral surface of the abdomen and a layer-by-layer skin incision 3 cm long was performed under local anesthesia. Group 2 - rats with natural wound healing for 10 days. Animals of group 3 were daily smeared with chitosan cream, 4 groups underwent daily photomodulation of the skin surface treated with methylene blue. The fifth group of rats, along with chitosan core and photomodulation, from the third day after the operation, received low-intensity exercise on a treadmill for 30 minutes. Wound healing was recorded by determining the area of the wound by photographing and histological examination of the skin and internal organs.

Obtained results: The best wound healing according to planimetry and histological examination was reliably noted in the 5th group during the complex treatment of the surgical wound.

Conclusions: The rehabilitation complex for large surgical wounds should include early local impact on the wound of physiotherapy procedures and physical exercises.

Author Biographies

G. Belov , International School of Medicine of the International University of Kyrgyzstan

Doctor of Medical Sciences, Professor, Head of the Department of Pathology

T. Uzakov , Kyrgyz State Medical Institute for Retraining and Advanced Studies

postgraduate student

J. Chyngyshova , Kyrgyz State Medical Institute for Retraining and Advanced Studies

Doctor of Medical Sciences, Head of the Department of Anesthesiology 


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